Volume 07 issue 03

Bakuchiol from psoralea corylifolia and its dermatological applications: a comprehensive review: Bakuchiol from psoralea corylifolia and its dermatological applications: a comprehensive review


The meroterpene bakuchiol has lately generated a lot of buzz in the beauty and medicine sectors. Although it has a wide geographical range, the seeds of the medicinal plant Psoralea corylifolia, which is native to Asia, are its principal source. Nevertheless, the low seed germination rates and significant seedling mortality put this therapeutic plant in jeopardy. Here, research documenting plant regeneration from root fragments is highlighted in a review paper. Then, because it looks so much like other species, we talk about and investigate a method that may be used to check if the plant is real and stop forgeries. We also provide a "green" extraction approach for bakuchiol and investigate potential chemical synthesis methods for bakuchiol. In addition, we detail the several biological functions of bakuchiol, focusing on those that affect the skin. Antifungal, antibacterial, antioxidant, anti-inflammatory, antiaging, depigmenting, and anticancer are some of bakuchiol's primary skin bioactivities. Nevertheless, novel skin delivery techniques that enable bakuchiol's encapsulation are necessary and advantageous due to its unique physicochemical characteristics. This review article also provides a thorough description of systems that are micro- or nano-sized and have medicinal or cosmetic uses. The use of bakuchiol in cosmetic and dermopharmaceutical formulations raises regulatory, metabolic, and toxicological problems that impact both the user and the environment. The dermatological uses of bakuchiol, a chemical isolated from Psoralea corylifolia, are discussed in detail in this article. Because of its antioxidant, anti-inflammatory, and anti-aging capabilities, bakuchiol has attracted interest as a possible natural substitute for retinol. Here we take a look at its molecular features, extraction techniques, and safety profiles. Also covered are the effects of bakuchiol on acne, hyperpigmentation, and wrinkles, among other dermatological issues. All things considered, the data show that bakuchiol may be a powerful and adaptable component in skincare products, which is great news for the development of all-natural skincare options.

  • Bakuchiol,
  • Psoralea Corylifolia,
  • Dermatological
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How to Cite

DR. TRIPTI BISARIA, D. T. B., & MR. KAMLESH KUMAR, M. K. K. (2024). Bakuchiol from psoralea corylifolia and its dermatological applications: a comprehensive review: Bakuchiol from psoralea corylifolia and its dermatological applications: a comprehensive review. International Journal of Multidisciplinary Research and Studies, 7(03), 01–15. Retrieved from

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